Health (PRISME)

  • Presentation
  • Activities
  • Members
  • Publications

The PRISME team is composed of physicists, biochemists, biologists and radiotherapists. We specialize in multidisciplinary research aimed at developing, optimizing and controlling innovative radiotherapies, whether it be hadrontherapy or therapies using radioactive ion-emitting elements or nanoparticles. These radiotherapies aim to improve the treatment of certain cancers by increasing the effect of ionizing radiation in the tumor while minimizing its harmful effects on healthy tissues.

Our multidisciplinary approach aims to quantify, understand and predict the effect of ionizing radiation on living organisms from processes induced at extremely short times (attosecond) at small scales (atomic nucleus) to long-term consequences (years) at the patient level.
We therefore design and carry out irradiation experiments on targets ranging from molecules or cells to small animals and patient samples (tumor, blood). These experiments feed an important part of our activity which consists in modeling the effects of radiation on living organisms.

One of the innovative techniques of radiotherapy is hadrontherapy, which is to send
an ion beam on the tumors to destroy them. We are working, in particular using simulations, data processing and predictions, to improve these systems by having on-line control over irradiation using dedicated detectors. These tools also have applications in imaging.

The activities can be divided into three research areas:

Axis 1 aims to develop simulations and detectors to control patient irradiation by detecting the particles emitted during hadrontherapy treatment. These developments also offer application prospects in the field of diagnostic imaging.

Axis 2 focuses on the development of multi-scale models and simulations to describe and predict the physical, chemical and biological processes induced by irradiation. It also develops irradiation and dosimetric control means for the measurement of radiobiological effects.

Axis 3 quantifies by experiment the effects induced by irradiation with molecular, cellular, multicellular, in-vitro or in-vivo systems. It focuses on the specificities of innovative radiotherapies and the personalization of care.

PERMANENTS:

NON-PERMANENTS:

- DOCTORANTS / DOCTORAL STUDENTS:

- CHERCHEURS NON-PERMANENTS / NON-PERMANENT RESEARCHERS:

Warning: Undefined property: stdClass::$facet_counts in /var/www/html/wp-content/plugins/hal/wp-hal.php on line 480

Warning: Attempt to read property "facet_fields" on null in /var/www/html/wp-content/plugins/hal/wp-hal.php on line 480
8785 documents

  • Albert M Sirunyan, Armen Tumasyan, Wolfgang Adam, Federico Ambrogi, Ece Asilar, et al.. Evidence for light-by-light scattering and searches for axion-like particles in ultraperipheral PbPb collisions at \sqrt{s_\mathrm{NN}} = 5.02 TeV. Physics Letters B, 2019, 797, pp.134826. ⟨10.1016/j.physletb.2019.134826⟩. ⟨hal-03171360⟩
  • Albert M Sirunyan, Armen Tumasyan, Wolfgang Adam, Federico Ambrogi, Ece Asilar, et al.. Charged-particle angular correlations in XeXe collisions at \sqrt{s_{_\mathrm{NN}}}= 5.44 TeV. Physical Review C, 2019, 100 (4), pp.044902. ⟨10.1103/PhysRevC.100.044902⟩. ⟨hal-02008883⟩
  • Albert M Sirunyan, Armen Tumasyan, Wolfgang Adam, Federico Ambrogi, Thomas Bergauer, et al.. Search for vector-like leptons in multilepton final states in proton-proton collisions at \sqrt{s} = 13 TeV. Physical Review D, 2019, 100 (5), pp.052003. ⟨10.1103/PhysRevD.100.052003⟩. ⟨hal-02154215⟩
  • Albert M Sirunyan, Armen Tumasyan, Wolfgang Adam, Federico Ambrogi, Ece Asilar, et al.. Measurement of electroweak WZ boson production and search for new physics in WZ + two jets events in pp collisions at \sqrt{s} = 13TeV. Phys.Lett.B, 2019, 795, pp.281-307. ⟨10.1016/j.physletb.2019.05.042⟩. ⟨hal-02000018⟩
  • Albert M Sirunyan, Armen Tumasyan, Wolfgang Adam, Federico Ambrogi, Thomas Bergauer, et al.. Search for physics beyond the Standard Model in events with overlapping photons and jets. Phys.Rev.Lett., 2019, 123 (24), pp.241801. ⟨10.1103/PhysRevLett.123.241801⟩. ⟨hal-02277910⟩
  • Albert M Sirunyan, Armen Tumasyan, Wolfgang Adam, Federico Ambrogi, Ece Asilar, et al.. Measurements of the pp \to WZ inclusive and differential production cross section and constraints on charged anomalous triple gauge couplings at \sqrt{s} = 13 TeV. JHEP, 2019, 04, pp.122. ⟨10.1007/JHEP04(2019)122⟩. ⟨hal-01999882⟩
  • Albert M Sirunyan, Armen Tumasyan, Wolfgang Adam, Federico Ambrogi, Ece Asilar, et al.. Search for single production of vector-like quarks decaying to a top quark and a W boson in proton-proton collisions at \sqrt{s} = 13 TeV. Eur.Phys.J.C, 2019, 79, pp.90. ⟨10.1140/epjc/s10052-019-6556-3⟩. ⟨hal-01890849⟩
  • Albert M Sirunyan, Armen Tumasyan, Wolfgang Adam, Federico Ambrogi, Ece Asilar, et al.. Search for a standard model-like Higgs boson in the mass range between 70 and 110 GeV in the diphoton final state in proton-proton collisions at \sqrt{s}= 8 and 13 TeV. Phys.Lett.B, 2019, 793, pp.320-347. ⟨10.1016/j.physletb.2019.03.064⟩. ⟨hal-01945227⟩
  • Albert M Sirunyan, Armen Tumasyan, Wolfgang Adam, Federico Ambrogi, Ece Asilar, et al.. Measurement of the top quark polarization and \mathrm{t\bar{t}} spin correlations using dilepton final states in proton-proton collisions at \sqrt{s} = 13 TeV. Phys.Rev.D, 2019, 100 (7), pp.072002. ⟨10.1103/PhysRevD.100.072002⟩. ⟨hal-02192539⟩
  • Albert M Sirunyan, Armen Tumasyan, Wolfgang Adam, Federico Ambrogi, Thomas Bergauer, et al.. Search for Higgs and Z boson decays to J/ψ or Y pairs in the four-muon final state in proton-proton collisions at s=13TeV. Phys.Lett.B, 2019, 797, pp.134811. ⟨10.1016/j.physletb.2019.134811⟩. ⟨hal-02154210⟩

Powered by HAL logo