Health (PRISME)
- Presentation
- Activities
- Members
- Publications
The PRISME team is composed of physicists, biochemists, biologists and radiotherapists. We specialize in multidisciplinary research aimed at developing, optimizing and controlling innovative radiotherapies, whether it be hadrontherapy or therapies using radioactive ion-emitting elements or nanoparticles. These radiotherapies aim to improve the treatment of certain cancers by increasing the effect of ionizing radiation in the tumor while minimizing its harmful effects on healthy tissues.
Our multidisciplinary approach aims to quantify, understand and predict the effect of ionizing radiation on living organisms from processes induced at extremely short times (attosecond) at small scales (atomic nucleus) to long-term consequences (years) at the patient level.
We therefore design and carry out irradiation experiments on targets ranging from molecules or cells to small animals and patient samples (tumor, blood). These experiments feed an important part of our activity which consists in modeling the effects of radiation on living organisms.
One of the innovative techniques of radiotherapy is hadrontherapy, which is to send
an ion beam on the tumors to destroy them. We are working, in particular using simulations, data processing and predictions, to improve these systems by having on-line control over irradiation using dedicated detectors. These tools also have applications in imaging.
The activities can be divided into three research areas:
Axis 1 aims to develop simulations and detectors to control patient irradiation by detecting the particles emitted during hadrontherapy treatment. These developments also offer application prospects in the field of diagnostic imaging.
Axis 2 focuses on the development of multi-scale models and simulations to describe and predict the physical, chemical and biological processes induced by irradiation. It also develops irradiation and dosimetric control means for the measurement of radiobiological effects.
Axis 3 quantifies by experiment the effects induced by irradiation with molecular, cellular, multicellular, in-vitro or in-vivo systems. It focuses on the specificities of innovative radiotherapies and the personalization of care.
NON-PERMANENTS:
- DOCTORANTS / DOCTORAL STUDENTS:
- CHERCHEURS NON-PERMANENTS / NON-PERMANENT RESEARCHERS:
- R. Tieulent. Low Mass Vector Mesons Production in
collisions at forward rapidity in the dimuon channel at 
= 200 and 510 GeV at RHIC. XXIV International Conference on Ultrarelativistic Nucleus-Nucleys Collisions Quark Matter 2014, May 2014, Darmstadt, Germany. ⟨in2p3-01018941⟩ - A. Uras. Prospects for the ALICE muon physics with the Muon Forward Tracker upgrade. XXIV International Conference on Ultrarelativistic Nucleus-Nucleys Collisions Quark Matter 2014, May 2014, Darmstadt, Germany. ⟨in2p3-01018940⟩
- D. Autiero. Neutrino interaction systematics for future experiments: The path forward. 9th International Workshop on Neutrino-Nucleus Interactions in the Few-GeV Region NuInt14, May 2014, Surrey, United Kingdom. ⟨in2p3-00999746⟩
- A. Cazes. The EDELWEISS Dark Matter search from phase 2 to phase 3. XXVIth Rencontres de Blois Particle Physics & Cosmologie, May 2014, Blois, France. ⟨in2p3-00994310⟩
- D. Sabes. L1 track triggering with associative memory for the CMS HL-LHC tracker. Workshop on Intelligent Trackers (WIT2014), May 2014, Philadelphie, United States. pp.C11014, ⟨10.1088/1748-0221/9/11/C11014⟩. ⟨in2p3-01117675⟩
- J J Li, W H Long, J Margueron, N van Giai. Relativistic Hartree-Fock-Bogoliubov predictions of superheavy magic nuclei. 11th International Spring Seminar on Nuclear Physics: Shell Model and Nuclear Structure : Achievements of the past two decades, May 2014, Ischia, Italy. pp.012006 ⟨10.1088/1742-6596/580/1/012006⟩. ⟨in2p3-01247457⟩
- G. de France, A. Blanc, F. Drouet, M. Jentschel, U. Köster, et al.. The EXILL campaign. 75 years of Nuclear Fission: Present Status and Future Perspective (Fission75), May 2014, Mumbai, India. pp.467-472, ⟨10.1007/s12043-015-1065-x⟩. ⟨in2p3-01203698⟩
- X. Wang, Gérard Panczer, D. de Ligny, Vincent Motto-Ros, J. Yu, et al.. Irradiated rare-earth-doped powellite single crystal probed by confocal Raman mapping and transmission electron microscopy. Journal of Raman Spectroscopy, 2014, 45 (5), pp.383-391. ⟨10.1002/jrs.4472⟩. ⟨in2p3-00991529⟩
- M. Gouzevitch. Measurements of photon and diphoton production processes at CMS. XXII. International Workshop on Deep-Inelastic Scattering and Related Subjects DIS2014, Apr 2014, Warsaw, Poland. ⟨in2p3-01011757⟩
- J. Marteau. Latest results in muon radiography applied to volcanology. Japan Geosciences Union (JpGU 2014), Apr 2014, Tokyo, Japan. ⟨in2p3-01019501⟩
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