Health (PRISME)

  • Presentation
  • Activities
  • Members
  • Publications

The PRISME team is composed of physicists, biochemists, biologists and radiotherapists. We specialize in multidisciplinary research aimed at developing, optimizing and controlling innovative radiotherapies, whether it be hadrontherapy or therapies using radioactive ion-emitting elements or nanoparticles. These radiotherapies aim to improve the treatment of certain cancers by increasing the effect of ionizing radiation in the tumor while minimizing its harmful effects on healthy tissues.

Our multidisciplinary approach aims to quantify, understand and predict the effect of ionizing radiation on living organisms from processes induced at extremely short times (attosecond) at small scales (atomic nucleus) to long-term consequences (years) at the patient level.
We therefore design and carry out irradiation experiments on targets ranging from molecules or cells to small animals and patient samples (tumor, blood). These experiments feed an important part of our activity which consists in modeling the effects of radiation on living organisms.

One of the innovative techniques of radiotherapy is hadrontherapy, which is to send
an ion beam on the tumors to destroy them. We are working, in particular using simulations, data processing and predictions, to improve these systems by having on-line control over irradiation using dedicated detectors. These tools also have applications in imaging.

The activities can be divided into three research areas:

Axis 1 aims to develop simulations and detectors to control patient irradiation by detecting the particles emitted during hadrontherapy treatment. These developments also offer application prospects in the field of diagnostic imaging.

Axis 2 focuses on the development of multi-scale models and simulations to describe and predict the physical, chemical and biological processes induced by irradiation. It also develops irradiation and dosimetric control means for the measurement of radiobiological effects.

Axis 3 quantifies by experiment the effects induced by irradiation with molecular, cellular, multicellular, in-vitro or in-vivo systems. It focuses on the specificities of innovative radiotherapies and the personalization of care.

PERMANENTS:

NON-PERMANENTS:

- DOCTORANTS / DOCTORAL STUDENTS:

- CHERCHEURS NON-PERMANENTS / NON-PERMANENT RESEARCHERS:

Warning: Undefined property: stdClass::$facet_counts in /var/www/html/wp-content/plugins/hal/wp-hal.php on line 480

Warning: Attempt to read property "facet_fields" on null in /var/www/html/wp-content/plugins/hal/wp-hal.php on line 480
8785 documents

  • E. Vient, L. Augey, B. Borderie, A. Chbihi, D. Dell'Aquila, et al.. Understanding the thermometry of hot nuclei from the energy spectra of light charged particles. The European physical journal. A, Hadrons and Nuclei, 2018, 54 (6), pp.96. ⟨10.1140/epja/i2018-12531-5⟩. ⟨hal-01833663⟩
  • Nicolas Bizot, Giacomo Cacciapaglia, Thomas Flacke. Common exotic decays of top partners. Journal of High Energy Physics, 2018, 06, pp.065. ⟨10.1007/JHEP06(2018)065⟩. ⟨hal-01757929⟩
  • S. Acharya, Jaroslav Adam, Dagmar Adamova, Jonatan Adolfsson, Madan Mohan Aggarwal, et al.. Longitudinal asymmetry and its effect on pseudorapidity distributions in Pb-Pb collisions at \sqrt{s_{NN}} = 2.76 TeV. Physics Letters B, 2018, 781, pp.20-32. ⟨10.1016/j.physletb.2018.03.051⟩. ⟨hal-01768021⟩
  • Albert M Sirunyan, Armen Tumasyan, Wolfgang Adam, Ece Asilar, Thomas Bergauer, et al.. Measurements of t\bar{t} cross sections in association with b jets and inclusive jets and their ratio using dilepton final states in pp collisions at \sqrt{s} = 13 TeV. Physics Letters B, 2018, 776, pp.355-378. ⟨10.1016/j.physletb.2017.11.043⟩. ⟨hal-01669734⟩
  • Shreyasi Acharya, Dagmar Adamova, Jonatan Adolfsson, Madan Mohan Aggarwal, Gianluca Aglieri Rinella, et al.. Production of ^{4}He and ^{4}\overline{\textrm{He}} in Pb-Pb collisions at \sqrt{s_{\mathrm{NN}}} = 2.76 TeV at the LHC. Nuclear Physics A, 2018, 971, pp.1-20. ⟨10.1016/j.nuclphysa.2017.12.004⟩. ⟨hal-01704400⟩
  • D. Adamová, Madan Mohan Aggarwal, Gianluca Aglieri Rinella, Michelangelo Agnello, Neelima Agrawal, et al.. J/\psi production as a function of charged-particle pseudorapidity density in p-Pb collisions at \sqrt{s_{\rm NN}} = 5.02 TeV. Physics Letters B, 2018, 776, pp.91-104. ⟨10.1016/j.physletb.2017.11.008⟩. ⟨hal-01669479⟩
  • A.M. Sirunyan, Armen Tumasyan, Wolfgang Adam, Federico Ambrogi, Ece Asilar, et al.. Identification of heavy-flavour jets with the CMS detector in pp collisions at 13 TeV. JINST, 2018, 13 (05), pp.P05011. ⟨10.1088/1748-0221/13/05/P05011⟩. ⟨hal-01797401⟩
  • Albert M Sirunyan, Armen Tumasyan, Wolfgang Adam, Federico Ambrogi, Ece Asilar, et al.. Charged-particle nuclear modification factors in XeXe collisions at \sqrt{s_{\mathrm{NN}}} = 5.44 TeV. Journal of High Energy Physics, 2018, 10, pp.138. ⟨10.1007/JHEP10(2018)138⟩. ⟨hal-01876247⟩
  • Albert M Sirunyan, Armen Tumasyan, Wolfgang Adam, Federico Ambrogi, Ece Asilar, et al.. Azimuthal correlations for inclusive 2-jet, 3-jet, and 4-jet events in pp collisions at \sqrt{s}= 13 TeV. European Physical Journal C: Particles and Fields, 2018, 78 (7), pp.566. ⟨10.1140/epjc/s10052-018-6033-4⟩. ⟨hal-01839648⟩
  • L. Kaya, A. Vogt, P. Reiter, C. Müller-Gatermann, M. Siciliano, et al.. Millisecond 23/{2}^{+} isomers in the N=79 isotones ^{133}\mathrm{Xe} and ^{135}\mathrm{Ba}. Physical Review C, 2018, 98 (5), pp.054312. ⟨10.1103/PhysRevC.98.054312⟩. ⟨hal-01952902⟩

Powered by HAL logo