Health (PRISME)

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  • Activities
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The PRISME team is composed of physicists, biochemists, biologists and radiotherapists. We specialize in multidisciplinary research aimed at developing, optimizing and controlling innovative radiotherapies, whether it be hadrontherapy or therapies using radioactive ion-emitting elements or nanoparticles. These radiotherapies aim to improve the treatment of certain cancers by increasing the effect of ionizing radiation in the tumor while minimizing its harmful effects on healthy tissues.

Our multidisciplinary approach aims to quantify, understand and predict the effect of ionizing radiation on living organisms from processes induced at extremely short times (attosecond) at small scales (atomic nucleus) to long-term consequences (years) at the patient level.
We therefore design and carry out irradiation experiments on targets ranging from molecules or cells to small animals and patient samples (tumor, blood). These experiments feed an important part of our activity which consists in modeling the effects of radiation on living organisms.

One of the innovative techniques of radiotherapy is hadrontherapy, which is to send
an ion beam on the tumors to destroy them. We are working, in particular using simulations, data processing and predictions, to improve these systems by having on-line control over irradiation using dedicated detectors. These tools also have applications in imaging.

The activities can be divided into three research areas:

Axis 1 aims to develop simulations and detectors to control patient irradiation by detecting the particles emitted during hadrontherapy treatment. These developments also offer application prospects in the field of diagnostic imaging.

Axis 2 focuses on the development of multi-scale models and simulations to describe and predict the physical, chemical and biological processes induced by irradiation. It also develops irradiation and dosimetric control means for the measurement of radiobiological effects.

Axis 3 quantifies by experiment the effects induced by irradiation with molecular, cellular, multicellular, in-vitro or in-vivo systems. It focuses on the specificities of innovative radiotherapies and the personalization of care.

PERMANENTS:

NON-PERMANENTS:

- DOCTORANTS / DOCTORAL STUDENTS:

- CHERCHEURS NON-PERMANENTS / NON-PERMANENT RESEARCHERS:
8787 documents

  • I. Laktineh. MSSM Msugra and the LSP at LEPII. Rencontres de Moriond : Electroweak Interactions and Unified Theories, Mar 2002, Les Arcs, France. pp.9. ⟨in2p3-00011727⟩
  • A. Deandrea. Charged Higgs in models with singlet neutrino in large extra dimensions. Rencontres de Moriond on Electroweak Interactions and Unified Theories 37, Mar 2002, Les Arcs, France. pp.4. ⟨in2p3-00019865⟩
  • N. Redon. La physique des ions lourds. Ecole IN2P3 De la Physique aux Detecteurs, Mar 2002, Roscoff, France. ⟨in2p3-00011994⟩
  • D. Guinet. Thermodynamique et transitions de phase. Journees de la Societe Francaise de Physique, Mar 2002, Caen, France. ⟨in2p3-00020317⟩
  • X. Artru. The transverse spin. Seminaire Rhodanien de Physique 10, Mar 2002, Via Gualino,Turin, Italy. pp.115-133. ⟨in2p3-00011808⟩
  • M. Oertel, M. Buballa. Color-flavor (Un)locking. International Workshop on Gross Properties of Nuclei and Nuclear Excitation 30, Mar 2002, Hirschegg, Germany. pp.7. ⟨in2p3-00011369⟩
  • O. Martineau, Angélique Benoit, L. Berge, A. Broniatowski, M. Caussignac, et al.. Dark matter search in the EDELWEISS experiment. 5th International UCLA Symposium on Sources and Detection of Dark Matter and Dark Energy in the Universe, Feb 2002, Marina Del Rey, CA, United States. pp.177-180. ⟨in2p3-00020052⟩
  • B. Farizon, M. Farizon, M.J. Gaillard, F. Gobet, J.P. Buchet, et al.. Cluster fragmentation and phase transition. 13th International Symposium on Atomic Cluster and Surface Physics (SASP 2002), Feb 2002, Going, Austria. ⟨in2p3-00019919⟩
  • B. Farizon, M. Farizon, M.J. Gaillard, F. Gobet, J.P. Buchet, et al.. Ionizing radiation action in water molecules. Symposium on RADiation Action in Biomolecules, Feb 2002, Going,Tirol, Austria. ⟨in2p3-00011975⟩
  • M. Bedjidian. Quarkonia in CMS. CMS Heavy Ion Workshop 6, Feb 2002, Boston, United States. ⟨in2p3-00021839⟩

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